CSIR IInd paper questions - Part 6

1. How the Pyruvate dehydrogenase (PDH), a key enzyme in citric acid cycle regulated? Name one metabolite involved in activation and one in deactivation of PDH, and mention their respective targets.

2. Show pictorially E. coli lac operon. What kind of regulation occurs in lac operon. Why?

a. What is popular plasma membrane model. Why is it so.

b. What are the four major phospholipids present in the plasma membrane of mammalian cells?

4. How different Cycloheximide and chloramphenicol in inhibiting protein synthesis ?

5. If you are given the genotypic frequencies of AABB, AaBB, aaBB, AABb, AaBb, aaBb, AAbb and Aabb in a mating experiment. How will you test whether the loci A and B are linked?