CSIR second paper questions - Part 4

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1. What are abzymes and ribozymes. Explain the differences and similarities?

2. What is the difference between climacteric and non-climacteric fruit? Give three examples?

3. What is "photorespiration" and why it is needed by plants?

4. How is the depletion of ozone affecting the plankton levels in the oceans?

5. Why virulence lost on sub-culturing?

CSIR second paper questions - Part 3

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1. a. What is the pH of Distilled water? Can give the reasons? 3M
b. What essential is the difference between distilled and deionized water? 3M

2. Can you draw competitive and noncompetitive inhibition Lineweaver-Burke Plots. Explain these different trends with respect to the mode of inhibition.


3. a. Explain the condition under which two species can co-exist in a single niche? Don’t they reject competitive exclusion principle.
b. Explain relationship between Biomass and productivity.
c. Explain adaptive radiation with example of Darwinian finches.

4. a. At pH 7, polylysine, which is a polypeptide in which all the residues are lysine, adopts a random coil conformation with no regular secondary structure, However, at pH 12 it is present as an α-helix. Explain.

Residue Number Phi (deg) Psi (deg)
1 -60 147
2 -49 -32
3 -67 -34
4 -58 -49
5 -66 -32
6 -82 -36
7 -69 -44
8 -61 -44
9 -72 -29
10 -66 -65
11 -67 -23



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The free energy diagram of Glycolysis shown in Figure. What do you confer or propose from this.

CSIR second paper questions - Part 1

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1. How many moles of CaCl2 would be used in the making of 5.00 x 102 cm3 of a 5.0 M solution?
2. Battery acid is generally 3 M H2SO4. Roughly how many grams of H2SO4 are in 400mL of this solution?
3.. Why does ice float on water?

4. Why must cells be small?
5. The RNA is Pre-Biotic? Justify your Answer.

6. How DNA triple helix stabilized. Assume, you have isolated a E coli mutant, which contains genome as triple helix. What way it will have different fundamental processes.

7. What is Collagen and a-keratin? Compare 1°, 2°, tertiary, and quaternary structures of collagen and a-keratin.

8. How do you determine shape and size of biomolecules in solution?

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Free Training/coaching for CSIR NET JRF exam

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Opportunity for PG students towards appearing for entrance examinations
Under the UGC XI Plan period, our department was considered by our university administration, for a training programme to the Post Graduate students on CSIR Net examinations type and also Department of Biotechnology sponsored Junior Research Fellowship Entrance examinations model.
The subject of training is exactly based on the CSIR syllabus.

This workshop programme is schedule to take place from 27th December 2010 to 16th January 2011 each day of 5 hours training. Those who are interested (II M.Sc., Biotechnology Students only) can apply in the proforma together with one page CV duly forwarded by the respective University HOD/ College Principal.

As this programme is UGC sponsored, students need not pay any payment towards this training. It is free of cost. The proforma includes:
1.Name;
2. Date of Birth;
3. Community;
4. Address for communication;
5. Mobile no;
6. e-mail ID;
7. Residence Land line No;
8. Present Course of study;
9. College Name;
10. University Name;
11. Native State;
12. Why you want to do Ph.D.;
13.What is your favored Ph.D. subject of study ;
14. Marks secured in B.Sc : %, I M.Sc : %
The completed proforma must reach the following address on or before 15th December 2010.

Details posted at jobsinsciences.com

CSIR study material - Research Methodology and Aptitude

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Research - Definitions

Action research is a methodology that combines action and research to examine specific questions, issues or phenomena through observation and reflection, and deliberate intervention to improve practice.

Applied research is research undertaken to solve practical problems rather than to acquire knowledge for knowledge sake.

Basic research is experimental and theoretical work undertaken to acquire new knowledge without looking for long-term benefits other than the advancement of knowledge.

Qualitative research is research undertaken to gain insights concerning attitudes, beliefs, motivations and behaviours of individuals to explore a social or human problem and include methods such as focus groups, in-depth interviews, observation research and case studies.

Quantitative research is research concerned with the measurement of attitudes, behaviours and perceptions and includes interviewing methods such as telephone, intercept and door-to-door interviews as well as self-completion methods such as mail outs and online surveys.

Three basic types of questions that research projects:

Descriptive:
When a study is designed primarily to describe what is going on or what exists. Public opinion polls that seek only to describe the proportion of people who hold various opinions are primarily descriptive in nature. For instance, if we want to know what percent of the population would vote for a BJP or Congress in the next election, we are simply interested in describing something.

Relational: When a study is designed to look at the relationships between two or more variables. A public opinion poll that compares what proportion of males and females say they would vote for a BJP or Congress candidate in the next election is essentially studying the relationship between gender and voting preference.

Causal: When a study is designed to determine whether one or more variables (e.g., a program or treatment variable) causes or affects one or more outcome variables. If we did a public opinion poll to try to determine whether a recent political advertising campaign changed voter preferences, we would essentially be studying whether the campaign (cause) changed the proportion of voters who would vote BJP or Congress (effect).

Time is an important element of any research design. The most fundamental distinctions in research design nomenclature: cross-sectional versus longitudinal studies. A cross-sectional study is one that takes place at a single point in time. In effect, we are taking a 'slice' or cross-section of whatever it is we're observing or measuring. A longitudinal study is one that takes place over time -- we have at least two (and often more) waves of measurement in a longitudinal design.

A variable is any entity that can take on different values. Anything that can vary can be considered a variable. For instance, age can be considered a variable because age can take different values for different people or for the same person at different times. Similarly, country can be considered a variable because a person's country can be assigned a value.

There is a distinction between an independent and dependent variable. In fact the independent variable is what you (or nature) manipulates -- a treatment or program or cause. The dependent variable is what is affected by the independent variable -- your effects or outcomes. For example, if you are studying the effects of a new educational program on student achievement, the program is the independent variable and your measures of achievement are the dependent ones.

A hypothesis is a specific statement of prediction. It describes in concrete (rather than theoretical) terms what you expect will happen in your study. Not all studies have hypotheses. Sometimes a study is designed to be exploratory.

CSIR study material - Research Methodology and Aptitude Part-2